An improved synthesis of 6- O -methyl-scutellarein through selective benzylation
JOURNAL OF CHEMICAL RESEARCH(2015)
摘要
An improved synthesis of 6-O-methyl-scutellarein is described. Benzyl bromide was selected to protect both the hydroxyl groups at C-4' and C-7 in scutellarein. The product was then methylated and deprotected to produce the target compound in high yield in four steps.
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关键词
scutellarin,scutellarein,6-O-methyl-scutellarein,metabolite,selective benzylation
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