Progressive severe B cell deficiency in pediatric Rubinstein-Taybi syndrome

Clinical Immunology(2016)

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摘要
•RSTS may be associated with severe B cell defects.•Expansion of CD21loCD38lo B cells may be present in RSTS.•Autoimmune cytopenias may complicate the clinical course of RSTS.
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关键词
Rubinstein-Taybi syndrome,B cells,Hypogammaglobulinemia,Autoimmune cytopenia
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