Multi-system state shifts and cognitive deficits induced by chronic morphine during abstinence.
Neuroscience Letters(2017)
摘要
•Morphine administration induced the withdrawal.•Obvious cognitive deficit was found in withdrawal in rats.•MEMRI maps the dysfunctional regions in withdrawal rats.•Withdrawal disturbs the brain function leading to muti-systems state shifts.
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关键词
Morphine,Manganese-enhanced MRI,Withdrawal,Cognitive
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