[Characteristic and clinical significance of DNA methyltransferase 3B overexpression in endometrial carcinoma].

Dong Ying,Zhou Mei,Ba Xiaojun,Si Jingwen,Li Wenting,Wang Ying,Li Dong,Li Ting

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences（2016）

引用 23|浏览4

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摘要

This study showed that the expression of DNMT3B in EC and NEC was different. DNMT3B overexpression in EC was associated with the worse clinicopathological variables and might have predictive value. The methylation status of EC and NEC maybe different. In addition, in EC, DNMT3B overexpression negatively correlated with ER or PR expression. In NEC, the correlation between DNMT3B and ER or PR status was not present.

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