GW26-e4566 Loss of Osteoglycin Promotes Angiogenesis in Limb Ischemia Mouse Model via Modulation of VEGF-VEGFR2 Signaling Pathway

Qihong WU,Yu Ma,Chengchao Ruan,Yan Yang,Qian Ge,Ke Zhang,Hui Jiang,Mona Hong,Pingjin Gao

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2015）

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摘要

Osteoglycin (OGN) plays important roles in cardiovascular disease. However, the relationship between OGN and angiogenesis remains unknown. Therefore, we sought to investigate the effect of OGN on ischemia-induced angiogenesis and address the underlying mechanisms.Expression of OGN on endothelial

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