Quality of life assessment in patients with metastatic colorectal cancer receiving maintenance therapy after first-line induction treatment: a preplanned analysis of the phase III AIO KRK 0207 trial.

Julia Quidde,S. Hegewisch-Becker,Ullrich Graeven,Christian Lerchenmüller, B. Killing, R. Depenbusch,Claus-Christoph Steffens,T. Lange,G. Dietrich,J. Stoehlmacher, A. Reinacher,Andrea Tannapfel,Tanja Trarbach,Norbert Marschner,H.-J. Schmoll,A. Hinke,Salah-Eddin Al-Batran,Dirk Arnold

Annals of Oncology（2016）

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摘要

The unique analysis, the first preplanned HRQOL analysis of the phase III AIO KRK 0207 trial, demonstrates that continuation of active maintenance treatment (FP/Bev or Bev alone) after induction treatment is not associated with a remarkable detrimental effect on HRQOL compared with treatment discontinuation. Median EORTC QLQ-C30 scores and deterioration rates did not differ between maintenance arms.

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关键词

colorectal cancer,maintenance treatment,quality of life

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