GW26-e4374 Tanshinone IIA Protects H9c2 Cells From Oxidative Stress-Induced Cell Death Via Up-Regulation of MicroRNA-133 and Akt Activation

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2015）

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摘要

In this study the cardioprotective effect and molecular mechanisms of tanshinone IIA were investigated.Cardiac H9c2 cells were cultured in Dulbeccou0027s modified Eagleu0027s medium supplemented with 10% fetal bovine serum. For transfection experiments, cells were transfected with 50 nM miR-133 mimic or

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