Good Syndrome Occurred in a Patient a Prolonged Time after Thymectomy: A Case Report and Literature Review of Cases in Japan

A 70-year-old Japanese woman was referred to our hospital with productive cough and recurrent respiratory infections. She underwent a thymectomy nine years previously for a thymoma. Based on a three-year history of repeated respiratory infections and the presence of hypogammaglobulinemia, a diagnosis of Good syndrome was made. We reviewed forty-six reported Japanese Good syndrome cases. The most commonly infected sites were the lungs, blood, and digestive tracts. Cases with preceding thymoma required a median time of three years (25th and 75th percentile: 1 and 7 years) until hypogammaglobulinemia emerged. The present case showed that Good syndrome should be considered even after a long time period following thymectomy.