Chronic hepatitis B: immune pathogenesis and emerging immunotherapeutics

Current Opinion in Pharmacology(2016)

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摘要
•HBV evades, subverts, activates and regulates various host immune components upon infection.•Immune concepts and terminologies in clinical CHB phenotypes need re-evaluation.•There are ongoing efforts in immunotherapeutic development to treat CHB.•A combined approach is likely needed to clear HBV and establish long term protective immunity.
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