Comment on: Early CSF and serum S 100B concentrations for outcome prediction in traumatic brain injury and subarachoid haemorrhage

BACKGROUND AND METHODS:In the letter the authors discuss the findings in Kellerman and co-worker's paper: Early CSF and Serum S 100B Concentrations for Outcome Prediction in Traumatic Brain Injury and Subarachoid Haemorrhage published in this journal. Among the findings reported in this paper is that an initial S 100B value of more than 0.7μg/l would strongly indicate a very poor prognosis. This finding is discussed. CONCLUSION:That a use of S 100B as a prognostic tool for clinical decision making is very doubtful and should most probably be refrained from.