Phenolic compounds from the roots of Ochna schweinfurthiana and their antioxidant and antiplasmodial activities

⿢Three new compounds namely 4⿴-methoxylophirone A (1); 4,4⿲-4⿴⿿trimethoxylophirone A (2) and (4E;7Z)-3,8-dicarboxy-1-(O-β-d-glucopyranosyl-(1⿿6)-O-β-d-glucopyranosyl-2,9-dihydroxyhexeicosa-4,7-diene (3) were isolated from the roots of Ochna schweinfurthiana along with six known compounds.⿢Some of the isolated compounds were evaluated for their antiplasmodial activity against the 3D7chloroquine-sensitive strain of Plasmodium falciparum and antioxidant activity was determined.⿢Compound 5 showed a prominent radical scavenging (SC50=0.17μM) and Ferric reducing-antioxidant power activity (214.32μg EAA/mg dw) and 1 showed good in vitro anti-plasmodial activity (IC50=08.43μM).