Discovery and Structure-Activity Relationships of a Novel Isothiazolone Class of Bacterial Type II Topoisomerase Inhibitors.
Ian R. Cooper, Andrew J. McCarroll,David McGarry,James Kirkham,Mark Pichowicz,Rolf Walker, Catherine Warrilow,Anne-Marie Salisbury,Victoria J. Savage,Emmanuel Moyo,Henry Forward,Jonathan Cheung,Richard Metzger, Zoe Gault,Gary Nelson,Diarmaid Hughes,Sha Cao,John Maclean,Cedric Charrier,Mark Craighead,Stuart Best,Neil R. Stokes,Andrew J. Ratcliffe Bioorganic & Medicinal Chemistry Letters（2016）
关键词
ESKAPE pathogens,Anti-infectives,Topoisomerases,DNA gyrase,Isothiazolone
AI 理解论文
溯源树
样例
