321 Development of Intrathecal Riluzole: A New Route of Administration for the Treatment of Amyotrophic Lateral Sclerosis Patients.

Juanmarco Gutierrez,Thais Federici, Bethany Peterson,Ray Bartus,Alexandre Bétourné,Nicholas M. Boulis

Neurosurgery（2016）

引用 9|浏览6

暂无评分

摘要

INTRODUCTION:Oral administration of riluzole is the only Food and Drug Administration-approved therapy for amyotrophic lateral sclerosis (ALS). However, per os riluzole therapy has shown modest efficacy and is limited by its negative impact on liver function. We hypothesize that intrathecal (IT) adm

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要