HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC PILOCYTIC ASTROCYTOMA

Neuro-oncology（2016）

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摘要

Introduction: Tumors with histological features of pilocytic astrocytoma but with increased mitotic activity and additional high grade features (i.e. microvascular proliferation, necrosis) have been designated anaplastic pilocytic astrocytomas (APA). Patients with such tumors are thought to have an [for full text, please go to the a.m. URL]

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关键词

Pilocytic astrocytoma,ATRX,Cancer research,Pathology,MAPK/ERK pathway,Necrosis,Mitosis,Gene,Biology,Cdkn2a b,Microvascular Proliferation

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