Prognostic Value of Proadrenomedulin in Severe Sepsis and Septic Shock Is Independent of Etiology and Focus of Infection

R Cicuendez, L Nogales,A Bueno,S Gonzalez De Zarate,D Calvo, C Andres, P Bueno, E Zarca,MF Muñoz, J Bermejo,JM Eiros, F Gandia, D Andaluz-Ojeda

Intensive Care Medicine Experimental（2015）

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摘要

Proadrenomedulin (proADM) is a novel prognostic biomarker employed in pneumonia and more recently in severe sepsis and septic shock. Release kinetics of proADM in this disease has not been studied. in this research we analyze the variation in plasma levels of this prohormone based upon the type of causative agent, the site of infection and the presence of renal failure.

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Pneumonia,Renal Failure,Plasmatic Level,Septic Shock,Causative Agent

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