Clinicopathological significance and concordance analysis of c-MET immunohistochemistry in non-small cell lung cancers: A meta-analysis

Pathology - Research and Practice(2016)

引用 35|浏览10
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摘要
•The estimated c-MET IHC positive rate was 44.0% in NSCLC.•The c-MET expression was significantly correlated with non-SCC and higher tumor stage.•There was significant correlation between c-MET positivity and poor overall survival.•The c-MET IHC showed high diagnostic accuracy for predicting c-Met genetic alteration.
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关键词
Non-small cell lung carcinoma,c-MET,Immunohistochemistry,Meta-analysis,Diagnostic test accuracy review
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