Concise syntheses of bridged morpholines

Andrey V. Zaytsev,James Pickles,Suzannah J. Harnor,Alistair P. Henderson, Mohammed Alyasiri,Paul G. Waddell,Celine Cano,Roger J. Griffin,Bernard T. Golding

RSC ADVANCES（2016）

引用 6|浏览33

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摘要

Concise and practical syntheses of 8-oxa-3-aza-bicyclo[3.2.1]octane and 9-oxa-3-aza-bicyclo[3.3.1]nonane are described starting from furan-2,5-dicarboxylic acid and 4H-pyran-2,6-dicarboxylic acid, respectively, and using a solvent-free step for a key cyclisation.

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