Transcriptional Interpretation Of Shh Morphogen Signaling: Computational Modeling Validates Empirically Established Models

DEVELOPMENT(2016)

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摘要
In an article published in Development titled ‘A theoretical framework for the regulation of Shh morphogen-controlled gene expression’, the Briscoe laboratory presented a mathematical model of the transcriptional interpretation of graded Shh signaling and bifunctional Gli transcription factors (
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