Clinical observation of interventional therapy of thyroid tumor by ~(32)Phosphorus-radiocolloid

Objective To observe the effects of interventional therapy on the thyroid tumor by intratumoral injection of32Phosphorus-radiocolloid(32P-colloidal) under ultrasonic guidance.Methods Patients with thyroid tumors who underwent intratumoral injection of32P-colloidal(32P-colloidal group,n = 30) and pure ethanol( control group,n = 30) under ultrasound guidance were selected.T he therapeutic effect and adverse reactions were recorded by follow-up after being treated for 2,4,6,and 8 months.Results Regular follow-up showed that the therapeutic effect of32P-colloidal group was correlated with the tumor size after being treated for 6 and 8 months( P = 0.042 and 0.019,respectively).T he therapeutic effect of32P-colloidal group was significantly better than that of the control group after being treated for 8 months( P = 0.011).T he main adverse reactions of32P-colloidal group were mild pain at tumors sites( 33.00%),local skin erubescence( 16.67%),and radiodermatitis( 6.70%).Conclusion T he interventional therapy of thyroid tumor by intratumoral injection of32P-colloidal under ultrasonic guidance is convenient and effective with less adverse reactions.T he therapeutic effect is correlated with the tumor size.