Differences in systemic immune function contribute to exacerbation susceptibility in COPD patients

Jasper Geerdink,Sami O. Simons,Rebecca Pike,J A. Wedzicha,Hans Stauss,Yvonne F. Heijdra,John R. Hurst

EUROPEAN RESPIRATORY JOURNAL（2015）

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摘要

The aim of the present study was to assess whether there are differences in systemic immune function that associate with exacerbation susceptibility in COPD patients. PBMC samples from patients recruited to the London COPD cohort were studied. 8 patients were classified as frequent exacerbators (FE, ≥3 exacerbations/year) and 16 as infrequent exacerbators (IE,

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关键词

COPD - exacerbations,Immunology,Systemic effect

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