Immune response after prolonged hyperoxic mechanical ventilation

    Hj Helmerhorst
    Hj Helmerhorst
    Laura R. A. Schouten
    Laura R. A. Schouten
    Dj Van Westerloo
    Dj Van Westerloo

    Critical Care, pp. 2482015.

    Cited by: 0|Bibtex|Views0|
    Keywords:
    Mechanical Ventilation Tidal Volume Bronchoalveolar Lavage Fluid Pulmonary Inflammation Anesthetize Mouse

    Abstract:

    Mechanical ventilation and hyperoxia independently promote pulmonary injury and inflammation. However, the time course of the immune response following concurrent exposure is unclear. The aim of this preclinical study was to study both time-dependent and dose-dependent effects of supplemental oxygen during prolonged ventilatory support on...More

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