Glucocorticoid-Regulated Kinase: Linking Azotemia and Muscle Wasting in CKD.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY（2016）
摘要
A reduction in the protein content of muscle, observably reflected as loss of muscle mass, is a frequent accompaniment of aging and inflammatory and catabolic diseases, including progressive CKD.[1][1],[2][2] In patients with CKD, aside from the risk of progression to ESRD, all-cause mortality is an
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关键词
Azotemia,CKD-induced myopathy,Glucocorticoid-related kinase-1,knockout mice
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