Clozapine-induced myoclonus: a case report and review of the literature.
THERAPEUTIC ADVANCES IN PSYCHOPHARMACOLOGY(2015)
摘要
We describe the case of a young man with treatment-resistant schizophrenia, who developed myoclonus during clozapine titration. This subsequently led to a full tonic-clonic seizure. Clozapine treatment can result in a range of seizure-like activity, the most wellknown being tonic-clonic seizures. This case highlights the importance of recognizing and treating clozapine-induced myoclonus, as it can herald the onset of a full seizure, even at low serum clozapine levels. We highlight the variety of ways myoclonus can present clinically and suggest treatment options.
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关键词
clozapine,myoclonus,seizures
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