Studies on the intestinal absorption of the alkaloids in the Gancaofuzi decoction in a Caco-2 cell culture system by UPLC-MS/MS analysis

Ru Ding,Yong Jian,Hong Kan,Zhongying Liu,Shu Liu,Zhiqiang Liu, Jun Zhou

Chinese Chemical Letters（2016）

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摘要

A UPLC–MS/MS based Caco-2 cell monolayer mode is used to determine whether intestinal absorption of alkaloids is influenced by the compatibility of four herbs in Gancaofuzi decoction.

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关键词

Gancaofuzi decoction,Caco-2 cell,Alkaloids,Combination,Ultra performance liquid chromatography coupled with tandem mass spectrometry (UPLC–MS/MS)

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