Effectiveness Of Anise Oil For Treatment Of Mild To Moderate Depression In Patients With Irritable Bowel Syndrome: A Randomized Active And Placebo-Controlled Clinical Trial
JOURNAL OF EVIDENCE-BASED INTEGRATIVE MEDICINE(2017)
摘要
Depression is a prevalent disorder among patients suffering from irritable bowel syndrome. The current study was performed to evaluate the effect of a traditional Persian medicine product, anise oil, in removing the symptoms of mild to moderate depression in patients with irritable bowel syndrome. In a randomized double-blinded active and placebo controlled clinical trial, 120 participants with mild to moderate depression according to the Beck Depression Inventory-II total scores were categorized into 3 equal groups and received anise oil, Colpermin, and placebo. The results at the end of trial (week 4) and follow-up (week 6) demonstrated significant priority against active and placebo groups. Although the mechanism is unknown yet, anise oil could be a promising choice of treatment for depressed patients with irritable bowel syndrome.
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关键词
depression, traditional Persian medicine, anise, irritable bowel syndrome
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