Accelerated progression of Hodgkin’s-like lymphomas in golli deficient SJL mice

•Golli KO SJL mice have an accelerated progression of Hodgkin’s like lymphoma.•CD44highCD62Llow effector/memory CD4+ T cells are accumulated in golli KO lymphoma.•Upregulation of regulatory cytokines in golli KO lymphoma infiltrated CD4+ T cells.•Increased Treg cell surface molecules on golli KO lymphoma infiltrated CD4+ T cells.•Increased IL-10 producing cells in golli KO mice prior to the onset of lymphoma.•Increased FoxP3+ Treg cells in golli KO mice prior to the onset of lymphoma.•Higher conversion of FoxP3+ Treg cells from golli KO T cells in vitro.