Prediction of neutralization of clotting effect of venom Bothrops pauloensis by aqueous extract of Hedychium coronarium (Zingeberaceae) through of regression models.

Envenomations with snakes Bothrops genus can cause dependency at the sting site, which are not reversed even after treatment with snake antivenoms. Incubation of the aqueous extract of Hedychium coronarium (Zingeberaceae) with snake venom Bothrops pauloensis in different concentrations was able to inhibit some enzymatic activities. This work has set a model of regression between concentrations of extract and clotting time (seconds). The adjusted model has captured about 96% of the total variation of clotting time.