Primary and booster vaccination with an inactivated poliovirus vaccine (IPV) is immunogenic and well-tolerated in infants and toddlers in China

Rongcheng Li,Chang Gui Li,Yanping Li,Youping Liu,Hong Zhao,Xiaoling Chen,Sherine Kuriyakose,Olivier Van Der Meeren,Karin Hardt,Marjan Hezareh,Sumita Roy-Ghanta

Vaccine（2016）

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摘要

•IPV safety and immunogenicity were assessed in the Chinese vaccination schedule.•IPV was non-inferior to Chinese OPV in terms of seroprotection rates.•IPV had a clinically acceptable safety profile in four studies.•IPV could feasibly be incorporated into Chinese vaccination schedule.

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关键词

Poliomyelitis,Poliovirus,Vaccine,Oral poliovirus vaccine,Inactivated poliovirus vaccine,Booster,China,Eradication

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