Metabolic profile of anhydrosafflor yellow B in rats by ultra-fast liquid chromatography/quadrupole time-of-flight mass spectrometry.

Shijun Yue,Liang Wu,Jun Wang,Yuping Tang,Cheng Qu,Xuqin Shi,Peng-Xuan Zhang,Yahui Ge,Yu-Jie Cao,Hanqing Pang,Chenxiao Shan,Xiaobin Cui,Li Qian,Jin-ao Duan

Journal of Chromatography B（2016）

引用 11|浏览25

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摘要

•Development of a UFLC/Qq-TOF–MS/MS method to study metabolism of AHSYB in rats.•The metabolic profile of AHSYB was characterized in detail for the first time.•A total of 22 metabolites and 11 metabolic pathways were found in vivo.•The results provide essential data for understanding in vivo process of AHSYB and further study on it.

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关键词

Carthamus tinctorius,Anhydrosafflor yellow B,AHSYB,Metabolic profile,UFLC,Qq-TOF–MS/MS

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