Impact of high-fat diet and vitamin D3 supplementation on aortic stenosis establishment in waved-2 epidermal growth factor receptor mutant mice

Bérénice Colleville,Nicolas Perzo,Guillaume Avinée,Anaïs Dumesnil,Frederic Ziegler,Paul Billoir,Hélène Eltchaninoff,Vincent Richard,Eric Durand

Journal of Integrative Medicine（2019）

引用 3|浏览9

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摘要

These results suggest that HFD and vitamin D supplementation have no effect in the waved-2 mouse model. This model essentially mimics AR and rarely AS. Further studies are needed to find a reliable animal model of AS.

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关键词

Experimental model,Epidermal growth factor receptor,Vitamin D3,High-fat diet,Aortic stenosis,Aortic regurgitation

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