Characterization of a novel antibacterial N-acyl amino acid synthase from soil metagenome.

Chang-Muk Lee,Su-Yeon Kim,Sang-Hong Yoon,Jung-Bong Kim, Yoon-Soo Yeo,Joon-Soo Sim,Bum-Soo Hahn,Dong-Gwan Kim

Journal of Biotechnology（2019）

引用 7|浏览12

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摘要

•Finding N-acyl amino acid synthase (NAS) from soil metagenome clones.•Heterologous expression of the nasYPL gene conferred antibacterial activities.•nasYPL has antibacterial fractions identified N-acyl tyrosine, N-acyl phenylalanine, and N-acyl leucine.•Expression of nasYPL by host-specific manner may provide antibacterial characteristics.

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关键词

Antibacterial agent,Lipoamino acid,Metagenome,N-acyl amino acid synthase

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