Origin of the T790M mutation and its impact on the clinical outcomes of patients with lung adenocarcinoma receiving EGFR-TKIs.

Yujie Dong,Zhen Zhou, Jianguo Wang,Li Ma,Zichen Liu,Yuxuan Wang,Jing Song,Shucai Zhang,Nanying Che

Pathology - Research and Practice（2019）

引用 5|浏览8

暂无评分

摘要

The ddPCR assay is an ultra-sensitive method to detect a minor amount of de novo T790M mutations in tumor samples. The de novo T790M mutation is a relatively unfavorable prognosis factor for patients receiving first-line TKIs treatment.

查看译文

关键词

Origin,T790M,Clinical outcome,Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs),Lung adenocarcinoma

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要