POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.
EBioMedicine（2019）
摘要
Our study highlights the pathological significance of aberrantly expressed POH1 in TGF-β signaling hyperactivation and aggressive progression in HCC.
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关键词
POH1,TGF-β signaling,TGF-β receptor,Hepatocellular carcinoma.
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