Impact of 3 Major Maintenance Immunosuppressive Protocols on Long-term Clinical Outcomes: Result of a Large Multicenter Italian Cohort Study Including 5635 Renal Transplant Recipients.

C Caletti,P Manuel Ferraro, A Corvo,G Tessari,S Sandrini,I Capelli,E Minetti,L Gesualdo,G Girolomoni,L Boschiero,A Lupo,G Zaza

Transplantation Proceedings（2019）

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摘要

•Calcineurin inhibitor+antimetabolite+steroid is still the “gold standard” in immunosuppressive therapy.•Mammalian target-of-rapamycin inhibitors (mTOR-Is), instead of antimetabolites, do not modify major long-term clinical outcomes.•mTOR-I+CNI represents a valuable immunosuppressive strategy in transplantation.

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关键词

major maintenance immunosuppressive protocols,italian cohort study,clinical outcomes,long-term

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