Regular crabmeat consumers do not show increased urinary cadmium or beta-2-microglobulin levels compared to non-crabmeat consumers.

•Cadmium exposure in regular versus non-crabmeat consumers was evaluated.•Volunteers who reported higher crabmeat intakes had higher blood cadmium levels.•Crabmeat consumers had similar urinary levels of cadmium and beta-2-microglobulin.•Crabmeat consumers showed no change in long-term cadmium exposure or liver toxicity.