Triggered doxorubicin release using redox-sensitive hyaluronic acid-g-stearic acid micelles for targeted cancer therapy.

•Reduction-sensitive HCS was synthesized for targeted delivery.•To prove reduction-sensitive effect of HCS, particle size and drug release behavior under GSH condition were investigated.•in vitro and in vivo study, anticancer effect of HCSD was accomplished at HCT116 and CT26 cell lines.•Site-specific tumor targeting effect of HCSD was proved by intracellular uptake, competition assay and in vivo fluorescence imaging.