DAN plays important compensatory roles in systemic-to-pulmonary shunt associated pulmonary arterial hypertension.

Liukun Meng,Xiaoyan Liu,Xiao Teng,Wen Yuan,Lihua Duan,Jian Meng,Jun Li,Zhe Zheng,Yingjie Wei,Shengshou Hu

Acta physiologica (Oxford, England)（2019）

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摘要

Compensatory decrease of DAN in hypertensive lungs may retard the deterioration of shunt-associated PAH, at least in part, by antagonizing BMP signaling pathway. Furthermore, DAN might be a potential biomarker for PAH/CHD. This article is protected by copyright. All rights reserved.

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关键词

DAN ,biomarker,pulmonary arterial hypertension,systemic-to-pulmonary shunt

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