Acquired thrombotic thrombocytopenic purpura in a child: rituximab to prevent relapse. A pediatric report and literature review.

Sabrina Mariani,Silvia M Trisolini,Saveria Capria,Maria L Moleti,Marta Chisini,Giancarlo Ferrazza,Mahnaz Shafii Bafti,Maria A Limongiello,Eleonora Miulli,Flora Peyvandi,Robin Foà,Anna M Testi

HAEMATOLOGICA（2018）

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摘要

Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy (TMA), characterized by peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and severe deficiency of a disintegrin and metalloproteinase with trombospondin type 1 motif, member 13 (ADAMTS13

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