Pre-Clinical Translation of Second Harmonic Microscopy of Meniscal and Articular Cartilage Using a Prototype Nonlinear Microendoscope.

Stephen J Baskey,Marco Andreana,Eric Lanteigne,Andrew Ridsdale,Albert Stolow,Mark E Schweitzer

IEEE Journal of Translational Engineering in Health and Medicine（2019）

引用 9|浏览19

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摘要

Previous studies using nonlinear microscopy have demonstrated that osteoarthritis (OA) is characterized by the gradual replacement of Type II collagen with Type I collagen. The objective of this study was to develop a prototype nonlinear laser scanning microendoscope capable of resolving the structural differences of collagen in various orthopaedically relevant cartilaginous surfaces. The current ...

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关键词

Microscopy,Optical fibers,Prototypes,Biomedical optical imaging,Optical imaging,Fiber nonlinear optics

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