Maresin1 regulates neutrophil recruitment and IL-10 expression in Aspergillus fumigatus keratitis

Qing Tang,Chengye Che,Jing Lin,Hong He,Wenyi Zhao,Leyu Lv,Guiqiu Zhao

International Immunopharmacology（2019）

引用 32|浏览16

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摘要

•Maresin1 alleviates corneal lesions caused by Aspergillus fumigatus in C57BL/6 mouse.•Maresin1 increases p-GSK3β levels to regulate CXCL1 and IL-10 expression in response to Aspergillus fumigatus infection.•Maresin1 inhibits neutrophil recruitment into corneal stroma in mouse Aspergillus fumigatus keratitis.

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关键词

Fungal keratitis,Aspergillus fumigatus,Maresin1,Cytokines,Inflammatory cells

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