HEMA modulates the transcription of genes related to oxidative defense, inflammatory response and organization of the ECM in human oral cells.

Renke Perduns,Joachim Volk,Peter Schertl,Gabriele Leyhausen,Werner Geurtsen

Dental Materials（2019）

引用 17|浏览15

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摘要

•HEMA induces genes of the oxidative defense machinery in both cell types after 24h.•HEMA concurrently modulates genes related to inflammation and ECM remodeling.•Regulation of some genes differed at 10mM HEMA compared to lower concentrations.

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关键词

HEMA,Oral keratinocytes,Gingival fibroblasts,Gene expression,Oxidative stress,Inflammation,ECM

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