Pro-inflammatory S100A11 is elevated in inflammatory myopathies and reflects disease activity and extramuscular manifestations in myositis.

Lucie Andrés Cerezo,Hana Hulejová,Barbora Šumová,Tereza Kropáčková,Olga Kryštůfková,Martin Klein,Heřman F Mann,Josef Zámečník,Ondřej Pecha,Karel Pavelka,Jiří Vencovský,Ladislav Šenolt

Cytokine（2019）

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摘要

•S100A11 accumulates in regenerating and necrotizing muscle fibres of myositis patients.•S100A11 is elevated in plasma of patients with DM and CAM.•Increased S100A11 reflects disease activity and extramuscular manifestations in DM.

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关键词

Calgizzarin,S100 proteins,Myositis,Inflammation,Disease activity

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