Unraveling Specific Brain Microstructural Damage in Moyamoya Disease Using Diffusion Magnetic Resonance Imaging and Positron Emission Tomography.

Shoko Hara,Masaaki Hori,Ryo Ueda,Shihori Hayashi,Motoki Inaji,Yoji Tanaka,Taketoshi Maehara,Kenji Ishii,Shigeki Aoki,Tadashi Nariai

Journal of Stroke and Cerebrovascular Diseases（2019）

引用 10|浏览21

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摘要

Chronic ischemia in patients with MMD may induce decreased neurite and axonal density, simplified network complexity, and may lead to neurocognitive dysfunction. The increased interstitial fluid accompanying hemodynamic impairment may not be identical to the decreased neurite density and might be driven by another mechanism.

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关键词

Moyamoya disease,ischemia,cerebral blood flow and metabolism,diffusion MRI,magnetic resonance imaging,cognition,cognitive impairment

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