LPS REMOVAL REDUCES CD80-MEDIATED ALBUMINURIA IN CRITICALLY ILL PATIENTS WITH GRAM-NEGATIVE SEPSIS

    American journal of physiology. Renal physiology, 2019.

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    Keywords:
    Acute kidney injuryAlbuminuriaCD80Chronic kidney diseaseSepsis

    Abstract:

    LPS-induced sepsis is a leading cause of acute kidney injury (AKI) in critically ill patients. LPS may induce CD80 expression in podocytes with subsequent onset of proteinuria, a risk factor for progressive chronic kidney disease (CKD) frequently observed after AKI. This study aimed to investigate the therapeutic efficacy of LPS removal i...More

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