Androgen induces olfactory expression of prostaglandin E 2 receptor Ep1 in the burrow-living fish Bostrychus sinensis.

The Journal of Steroid Biochemistry and Molecular Biology(2019)

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摘要
•Androgens stimulated the expression of ep1 in the olfactory rosette of B. sinensis.•The stimulatory effect of androgens on ep1 expression was mediated by Ar.•The expression level of arα increased with spermatogenesis.•Activated Arα transactivated the ep1 promoter in HEK293T cells.•Some OSNs exhibited co-localization of arα mRNAs and Ep1 proteins.
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关键词
Bostrychus sinensis,Pheromone,Olfactory rosette,Prostaglandin E2 receptor,Androgen
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