MicroRNA-218 promotes early chondrogenesis of mesenchymal stem cells and inhibits later chondrocyte maturation.

Song Chen,Zhenyu Xu,Jiahua Shao,Peiliang Fu,Haishan Wu

BMC biotechnology（2019）

引用 30|浏览30

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摘要

Our study suggests that miR-218 contributes to early chondrogenesis while suppressing later chondrocyte maturation. The miR-218-HPGD pathway offers us a perspective into how SDSCs differentiate into chondrogenic cells.

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关键词

Articular cartilage,Chondrocyte maturation,Chondrogenesis,Mesenchymal stem cells,microRNA-218

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