Phosphoproteomic and transcriptomic analyses reveal multiple functions for Aspergillus nidulans MpkA independent of cell wall stress.

Cynthia L Chelius,Liliane F C Ribeiro,Walker Huso,Jyothi Kumar,Stephen Lincoln,Bao Tran,Young Ah Goo,Ranjan Srivastava,Steven D Harris,Mark R Marten

Fungal Genetics and Biology（2019）

引用 7|浏览30

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摘要

•Phosphoproteomics and transcriptomics revealed the broad cellular role of MpkA.•An mpkA deletion mutant had weaker walls and a higher branching rate.•MpkA appears to play a role in iron metabolism.•Other connected pathways include ROS/NOX, autophagy, and polyketide synthesis.

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关键词

Aspergillus nidulans,MpkA,Multi-omics,Cell wall,Iron regulation,Branching

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