Specific T-cell receptor gene transfer enhances immune response: A potential therapeutic strategy for the control of human cytomegalovirus infection in immunocompromised patients

Cellular Immunology(2019)

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摘要
•VSTs could be generated by transfer of TCR genes into PBMCs from donors and patients.•The generation of functional T cells varied among transduction of different PBMCs.•TCR gene transfer is a potential therapeutic strategy for HCMV controlling.
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关键词
HCMV,SFFV,TCR,IFN-γ,HSCT,ELISPOT,VSTs
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