poreTally: run and publish de novo Nanopore assembler benchmarks.

BIOINFORMATICS(2019)

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摘要
Nanopore sequencing is a novel development in nucleic acid analysis. As such, nanopore-sequencing hardware and software are updated frequently and extensively, which quickly renders peer-reviewed publications on analysis pipeline benchmarking efforts outdated. To provide the user community with a faster, more flexible alternative to peer-reviewed benchmark papers for de novo assembly tool performance we constructed poreTally, a comprehensive benchmarking tool. poreTally automatically assembles a given read set using several often-used assembly pipelines, analyzes the resulting assemblies for correctness and continuity, and finally generates a quality report, which can immediately be published on Github/Gitlab. Availability and implementation poreTally is available on Github at https://github.com/ cvdelannoy/poreTally, under an MIT license. Supplementary information Supplementary data are available at Bioinformatics online.
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