A Cluster of Cefepime-induced Neutropenia during Outpatient Parenteral Antimicrobial Therapy.

Kap Sum Foong,Kevin Hsueh,Thomas C Bailey,Lan Luong,Ayesha Iqbal,Christine Hoehner,Lee Connor,Ed Casabar,Michael Lane,Yvonne Burnett,David Ritchie,Tamara Krekel, Helen Newland, Lori Weilmuenster, Brett Heuring,Michael J Durkin,Yasir Hamad

CLINICAL INFECTIOUS DISEASES（2019）

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摘要

A cluster of cefepime-induced neutropenia (CIN) was identified from June 2017 to May 2018 in a regional outpatient parenteral antimicrobial therapy population. Our data suggest prolonged courses of cefepime (>= 2 weeks), administered by rapid intravenous push, were associated with a higher risk of CIN.

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关键词

cefepime,cefepime-induced neutropenia,drug-induced neutropenia,adverse drug event,OPAT

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